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Catalyze Reactions Explained: Quicken, Aggravate & Spread

Quick Answer

The Three Reactions

ReactionTriggerEffect
QuickenDendro or Electro hits target carrying the other elementApplies Quicken Aura (purple), no direct DMG, lasts ~4 s
AggravateElectro DMG hits a Quicken-affected targetAdds 1.15× Level Multiplier to base DMG (L90 zero-EM = 1664)
SpreadDendro DMG hits a Quicken-affected targetAdds 1.25× Level Multiplier to base DMG (L90 zero-EM = 1809)

Damage Formula

Aggravate/Spread are additive reactions — the bonus is added to the base DMG bracket, not a separate multiplier:

Final DMG = (ATK × Skill Multiplier + Catalyze Bonus) × (1 + DMG Bonus) × (1 + Crit DMG) × Resistance × DEF Reduction

Where: Catalyze Bonus = Level Base × Reaction Multiplier × [1 + (5×EM)/(EM+1200)]

LevelLevel BaseAggravate (0 EM)Spread (0 EM)
80134415461680
90144716641809

EM has steep diminishing returns: 300 EM = +16.7%, 400 EM = +19.4%, 500 EM = +20.8%. 300 EM is the sweet spot.

Why the Aura Persists

Aggravate and Spread consume only the incoming elemental application, not the Quicken Aura. With fast enough application, Quicken can persist 8–10+ seconds on a target, allowing repeated triggers.

Artifact Sets

Set4pc BonusBest For
Thundering Fury+20% Aggravate DMGFischl, Keqing (Electro carries)
Deep Tangle (4pc)+40% DMG vs Quicken/Electro-Charged/Bloom targetsAlhaitham, Tighnari (Dendro carries)
Honor of King 4pcTeam DMG +20% for 40 s after EWriothesley / Bennett support slots

Team Compositions

Aggravate Team (Electro carry)

Fischl (Aggravate main) + Nahida (Dendro appl. + EM convert) + Xingqiu/Kazuha + Zhongli/Kokomi

Spread Team (Dendro carry)

Alhaitham (Spread main) + Fischl/Yae (Electro appl.) + Kazuha + Kokomi/Zhongli

FAQ

What is the difference between Aggravate and Spread?

Aggravate is triggered by Electro DMG on a Quicken target (+1.15×). Spread is triggered by Dendro DMG on a Quicken target (+1.25×). Spread has a higher base multiplier but fewer strong Dendro carries.

Does Catalyze scale with Elemental Mastery?

Yes. The formula is 5×EM/(1200+EM). At 300 EM you get +16.7%, at 400 EM +19.4%. Diminishing returns are steep — 300 EM is usually the cap.

How long does the Quicken Aura last?

Base duration is ~4 s, refreshed by new Dendro/Electro applications. Because Aggravate/Spread do not consume it, a fast-application team can keep Quicken up for 8–10+ seconds.

Does Catalyze benefit from resistance shreds?

Yes. The flat bonus enters the base DMG bracket, so Kazuha's shred or Zhongli's C6 shred applies to the full value.

Does Catalyze benefit from Crit?

Yes. Since the bonus is added to the base bracket before crit is rolled, a critical hit still multiplies the full (base + Catalyze bonus) by 1 + Crit DMG.

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